Delayed neuronal death

@article{Kirino2000DelayedND,
  title={Delayed neuronal death},
  author={Takaaki Kirino},
  journal={Neuropathology},
  year={2000},
  volume={20}
}
  • T. Kirino
  • Published 2000
  • Biology, Medicine
  • Neuropathology
A brief, transient episode of cerebral ischemia causes selective loss of CA1 pyramidal cells in the hippocampus. Interestingly, it takes 2–3 days for the neuronal damage of CA1 to become morphologically obvious; hence, the term ‘delayed neuronal death’ was coined to describe this phenomenon. Approximately two decades after it was first recognized, the precise mechanism of delayed neuronal death is not yet fully understood. The most widely supported explanation is the glutamate‐Ca2+ theory, in… Expand
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