Delayed inflammatory mRNA and protein expression after spinal cord injury

  title={Delayed inflammatory mRNA and protein expression after spinal cord injury},
  author={Kimberly R Byrnes and Patricia M. Washington and Susan Knoblach and Eric P. Hoffman and Alan I. Faden},
  booktitle={Journal of Neuroinflammation},
Spinal cord injury (SCI) induces secondary tissue damage that is associated with inflammation. We have previously demonstrated that inflammation-related gene expression after SCI occurs in two waves - an initial cluster that is acutely and transiently up-regulated within 24 hours, and a more delayed cluster that peaks between 72 hours and 7 days. Here we extend the microarray analysis of these gene clusters up to 6 months post-SCI. Adult male rats were subjected to mild, moderate or severe… CONTINUE READING
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AI: Expression of two temporally distinct microgliarelated gene clusters after spinal cord injury

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