Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis.

@article{Ikewaki2005DelayedIV,
  title={Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis.},
  author={Katsunori Ikewaki and Juergen R Schaefer and Michael E. Frischmann and Keio Okubo and Tatsuo Hosoya and Seibu Mochizuki and Benjamin Dieplinger and Evi Trenkwalder and Horst Schweer and Florian Kronenberg and Paul A. Koenig and Hans Dieplinger},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2005},
  volume={25 12},
  pages={
          2615-22
        }
}
OBJECTIVE Premature cardiovascular disease is the leading cause of death in patients with end-stage renal disease treated by hemodialysis (HD). Low-density lipoprotein (LDL) levels are not generally increased in HD patients, but their LDL metabolism is still poorly understood. We therefore investigated the in vivo metabolism of apoB-containing lipoproteins in two different ethnic populations of HD patients and controls. METHODS AND RESULTS We performed stable isotope kinetic studies using a… CONTINUE READING

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