Delayed hypersensitivity to tetrazepam

@article{Blanco1997DelayedHT,
  title={Delayed hypersensitivity to tetrazepam},
  author={R Blanco and M L D{\'i}ez-G{\'o}mez and G. Gala and Santiago Quirce},
  journal={Allergy},
  year={1997},
  volume={52}
}
air or washing hands with cold water (< 10°C) resulted in the rapid induction of urticarial lesions. After all three wasp stings, she had developed only a moderate local reaction to the sting. Treatment with ketotifen was begun without significant effect on the symptoms. Physical examination showed no abnormalities. The ice-cube test on the volar forearm was positive. All other laboratory tests performed to rule out an underlying factor, including CBC, ESR, CRP ANA, rheumatoid factor… 

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References

SHOWING 1-10 OF 11 REFERENCES
Cold urticaria. Immunologic studies.
TLDR
Absorption studies showed that the passive transfer activity could be removed from the four serum specimens by monospecific antisersum to IgE but not by antiserum to any of the other immunoglobulins, quite similar to those of IgE skin-sensitizing antibodies.
Delayed cell‐mediated hypersensitivity to tetrazepam
TLDR
A 59-year-old man, with degenerative arthritis, was treated daily with 1 capsule of Myolastan® (50 mg tetrazepam) and developed an itchy maculopapular rash and tightness of the chest, without wheezing.
Tetrazepam allergy detected by patch test
Case no. 1. A 71-year-old man, with cervical arthralgia for 2 years, was successfully treated with 50 mg ofMyolastan® (tetrazepam) daily, taken at night, and 16 mg of Fidium® (betahistidine
Tetrazepam allergy once more detected by patch test
In February 1989, a 63-year-old man, with lumbar intervertebral degenerative arthritis, presented with maculopapular to purpuric lesions on the legs, which had appeared some days after the
Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria.
TLDR
All patients with ACU with active histories of cold urticaria are at risk to develop systemic reactions to cold and should therefore refrain from participating in aquatic activities, and high-risk patients should receive prophylactic medications that are effective in suppressing this disorder.
Tetrazepam: an allergen with several clinical expressions
TLDR
Positive reactions to nickel sulfate and all 3 dilutions of ceftiofur sodium were obtained and dermatitis affected both eyelids in a chicken vaccinator.
Cross‐reactive Type IV hypersensitivity reactions to benzodiazepines revealed by patch testing
TLDR
The 3 patients who reacted only to their own epoxy resin underline the importance of patch testing patients to their Own epoxy resins when investigating occupational cases and may not always be standard (diglycidyl ether of bisphenol A).
Occurrence of cold urticaria during venom desensitization.
Occurrence of Cold Urticaria during Venom Desensitization F. Francine Anfosso-Capra F. Francois Philip-Joet M. Martine Reynaud-Gaubert A. Alain Arnaud INSERM U 270, Faculté de Médecine Nord; Service
Cross - reactive type IV hypersensitivity to benzodiazepines revealed by patch testing
  • Contact Dermatitis
  • 1995
Crossreactive type IV hypersensitivity to benzodiazepines revealed by patch testing. Contact Dermatitis 1995;33:356
  • 1995
...
1
2
...