Delayed functional maturation of human neuronal progenitor cells in vitro.

@article{Lepski2011DelayedFM,
  title={Delayed functional maturation of human neuronal progenitor cells in vitro.},
  author={Guilherme Alves Lepski and Jaroslaw Maciaczyk and Cinthia Elim Jannes and Donata Maciaczyk and Josef Bischofberger and Guido Nikkhah},
  journal={Molecular and cellular neurosciences},
  year={2011},
  volume={47 1},
  pages={36-44}
}
INTRODUCTION Differentiation of neuronal progenitor cells (NPCs) in vitro into functional neurons is dependent on a complex cascade of molecular signaling pathways, many of which remain unknown. More specifically, in human NPCs the relationship between the expression of typical neuronal marker proteins and functional properties, such as firing action potential and synaptic transmission, is not well understood. In the present report, the immunocytochemical, morphological and electrophysiological… CONTINUE READING

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