Delayed development of ventricular ectopic rhythms following experimental coronary occlusion.

@article{Harris1950DelayedDO,
  title={Delayed development of ventricular ectopic rhythms following experimental coronary occlusion.},
  author={Adam S. Harris},
  journal={Circulation},
  year={1950},
  volume={1 6},
  pages={1318-28}
}
Following aseptic occlusion of the anterior descending artery of the dog's heart ectopic ventricular tachycardia develops after a latency of four and one-half to eight hours, and persists for two to four days. Large gross infarcts are found in all hearts. The duration of latency of onset of major ectopic activity approximates the minimal period of ischemia required to produce histologic signs of necrosis. It is suspected that products or processes of necrosis have excitatory effects on tissues… CONTINUE READING