Delayed de-induction of CYP2C9 compared to CYP3A after discontinuation of rifampicin: Report of two cases


OBJECTIVE Timely dose reduction of concomitant medications is important after withdrawal of rifampicin, a CYP inducer. However, little is known about the differences in the time course of deinduction for various CYP isoforms. To clarify the time courses of deinduction of CYP2C9 and -CYP3A activities after rifampicin withdrawal, we monitored these enzyme… (More)
DOI: 10.5414/CP202764


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