Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury.

@article{Wu2012DelayedCC,
  title={Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury.},
  author={Junfang Wu and Bogdan A Stoica and Michael Dinizo and Ahdeah Pajoohesh-Ganji and Chunshu Piao and Alan I. Faden},
  journal={Cell cycle},
  year={2012},
  volume={11 9},
  pages={1782-95}
}
Traumatic spinal cord injury (SCI) causes tissue loss and associated neurological dysfunction through mechanical damage and secondary biochemical and physiological responses. We have previously described the pathobiological role of cell cycle pathways following rat contusion SCI by examining the effects of early intrathecal cell cycle inhibitor treatment initiation or gene knockout on secondary injury. Here, we delineate changes in cell cycle pathway activation following SCI and examine the… CONTINUE READING
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