Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure.

@article{Franciscato2011DelayedBC,
  title={Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure.},
  author={Carina Franciscato and Luc{\'e}lia Moraes-Silva and F{\'a}bio Andrei Duarte and Cl{\'a}udia Sirlene Oliveira and Rafael Porto Ineu and Erico Marlon Moraes Flores and Valderi Luiz Dressler and Nilce Coelho Peixoto and Maria Ester Pereira},
  journal={Ecotoxicology and environmental safety},
  year={2011},
  volume={74 3},
  pages={480-6}
}
This work evaluated the delayed effects of mercury and the effectiveness of zinc in preventing such effects. Pups were pre-treated with 1 daily dose of ZnCl(2) (27 mg/kg/day, by subcutaneous injections) from 3rd to 7th postnatal day and received 1 daily dose of 5 mg/kg of HgCl(2), for 5 subsequent days (8-12 days old). Animals were euthanized 21 days after the end of Hg-exposure. Porphobilinogen-synthase activity as well as zinc and mercury contents was determined in the liver and kidneys… CONTINUE READING

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