Delayed K+ current and external K+ in single cardiac Purkinje cells.

@article{Scamps1989DelayedKC,
  title={Delayed K+ current and external K+ in single cardiac Purkinje cells.},
  author={Fr{\'e}d{\'e}rique Scamps and Edward E. Carmeliet},
  journal={The American journal of physiology},
  year={1989},
  volume={257 6 Pt 1},
  pages={
          C1086-92
        }
}
The effect of external K+ on the delayed K+ current was investigated in rabbit single Purkinje cells. Whole cell voltage clamp and intracellular dialysis were used. At K+ concentrations less than 1 mM the kinetics of the delayed K+ current were not changed, but the conductance was markedly reduced. This effect was due to a direct change at an extracellular site and not due to secondary changes in intracellular Na+ or Ca2+ concentrations. A rise in intracellular Na+ or Ca2+ rather increased the… CONTINUE READING
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