Delay in the development of amygdala kindling following treatment with 3,3'-iminodipropionitrile.


A disruption in cognitive function and induction of astrogliosis in the brain have been reported as neurotoxic effects of 3-3'-iminodipropionitrile (IDPN). Kindling is a model of synaptic plasticity that produces functional and structural alterations in brain that may encompass those underlying learning and memory. We examined kindling development in rats… (More)


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