Delay and trace fear conditioning in C57BL/6 and DBA/2 mice: issues of measurement and performance.

@article{Tipps2014DelayAT,
  title={Delay and trace fear conditioning in C57BL/6 and DBA/2 mice: issues of measurement and performance.},
  author={Megan E Tipps and Jonathan D Raybuck and Kari J. Buck and K Matthew Lattal},
  journal={Learning & memory},
  year={2014},
  volume={21 8},
  pages={380-93}
}
Strain comparison studies have been critical to the identification of novel genetic and molecular mechanisms in learning and memory. However, even within a single learning paradigm, the behavioral data for the same strain can vary greatly, making it difficult to form meaningful conclusions at both the behavioral and cellular level. In fear conditioning, there is a high level of variability across reports, especially regarding responses to the conditioned stimulus (CS). Here, we compare C57BL/6… CONTINUE READING