Deiodination activity in extrathyroidal tissues of the atlantic hagfish, Myxine glutinosa.

  title={Deiodination activity in extrathyroidal tissues of the atlantic hagfish, Myxine glutinosa.},
  author={J M McLeese and Glenda M. Wright and John H. Teeter Ronald E. Thresher Daniel M. Ware George Youson and J Geoffrey Eales},
  journal={The Journal of experimental zoology},
  volume={287 6},
We measured low substrate (<1 nM) thyroid hormone (TH) deiodination activities in liver, muscle, intestine, and brain microsomes of Atlantic hagfish fasted for 2 weeks and found extremely low thyroxine (T(4)) outer-ring deiodination (T(4)ORD) and inner-ring deiodination (T(4)IRD) as well as 3,5,3'-triiodothyronine (T(3)) IRD activities. T(3)ORD, 3',5'-triiodothyronine (rT(3)) ORD and rT(3)IRD activities were undetectable. Hagfish deiodinating pathways resembled those of teleosts in requiring a… CONTINUE READING


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