Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning.

@article{Thom1992DehydrogenaseCT,
  title={Dehydrogenase conversion to oxidase and lipid peroxidation in brain after carbon monoxide poisoning.},
  author={Stephen R. Thom},
  journal={Journal of applied physiology},
  year={1992},
  volume={73 4},
  pages={
          1584-9
        }
}
The conversion of xanthine dehydrogenase to xanthine oxidase and lipid peroxidation were measured in brain from carbon monoxide- (CO) poisoned rats. Sulfhydryl-irreversible xanthine oxidase increased from a control level of 15% to a peak of 36% over the 90 min after CO poisoning, while the conjugated diene level doubled. Reversible xanthine oxidase was 3-6% of the total enzyme activity over this span of time but increased to 31% between 90 and 120 min after poisoning. Overall, reversible and… CONTINUE READING

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