Dehydroepiandrosterone replacement in healthy men with age-related decline of DHEA-S: effects on fat distribution, insulin sensitivity and lipid metabolism.

@article{Jdrzejuk2003DehydroepiandrosteroneRI,
  title={Dehydroepiandrosterone replacement in healthy men with age-related decline of DHEA-S: effects on fat distribution, insulin sensitivity and lipid metabolism.},
  author={Diana Jędrzejuk and Marek Mędraś and Andrzej Milewicz and Marek Demissie},
  journal={The aging male : the official journal of the International Society for the Study of the Aging Male},
  year={2003},
  volume={6 3},
  pages={151-6}
}
Many animal and human studies show that supraphysiological doses of dehydroepiandrosterone (DHEA) can influence body composition and carbohydrate and lipid metabolism. Most studies have concentrated on women and have not been randomized, thus creating controversial results. With this in mind, we designed a cross-over double-blind placebo-controlled study of 12 men aged 59.0 +/- 4.8 years, who received either 50 mg/24 h DHEA or placebo for 3 months to assess the influence of DHEA on the content… CONTINUE READING

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