Dehydroepiandrosterone (DHEA) and systemic lupus erythematosus.

  title={Dehydroepiandrosterone (DHEA) and systemic lupus erythematosus.},
  author={R. W. Derksen},
  journal={Seminars in arthritis and rheumatism},
  volume={27 6},
  • R. W. Derksen
  • Published 1998 in Seminars in arthritis and rheumatism
OBJECTIVE This study was performed to evaluate in vivo and in vitro data on the effects of the adrenal steroid dehydroepiandrosterone (DHEA) with emphasis on its potential use in the treatment of systemic lupus erythematosus (SLE). METHODS The literature dealing with DHEA was reviewed. RESULTS Initially, research on DHEA focused on effects of DHEA in relation to obesity. Over the past decade, research stimulated by associations between the physiological decline in DHEA and aging… CONTINUE READING
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