Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.

  title={Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.},
  author={Rihab F. Angawi and Barbara Calcinai and Carlo Cerrano and Henny Adeleida Dien and Ernesto Fattorusso and Fernando Scala and Orazio Taglialatela‐Scafati},
  journal={Journal of natural products},
  volume={72 12},
The chlorinated polyene aurantoic acid (1) and the 4-methylene sterol dehydroconicasterol (2) were isolated from the Indonesian sponge Theonella swinhoei, and their structures were elucidated by interpretation of spectroscopic data. Aurantoic acid is a unique member in the class of naturally occurring conjugated polyene derivatives, while dehydroconicasterol is the likely biogenetic precursor of the major Theonella 4-methylene sterols. 
4-Methylenesterols from a Sponge Theonella swinhoei
Three new 4-methylenesterols, theonellasterol K, acetyltheonellastersol and acetyldehydroconicasterol were isolated from the sponge Theonella swinhoei and the structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues.
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Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.
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