Degree of participation of exogenous thymidine in the overall deoxyribonucleic acid synthesis in Escherichia coli.

@article{ROSENBAUMOLIVER1972DegreeOP,
  title={Degree of participation of exogenous thymidine in the overall deoxyribonucleic acid synthesis in Escherichia coli.},
  author={D. ROSENBAUM-OLIVER and Stephen Zamenhof},
  journal={Journal of bacteriology},
  year={1972},
  volume={110 2},
  pages={585-91}
}
Utilization of labeled exogenous deoxythymidine (TdR) for deoxyribonucleic acid (DNA) synthesis is widely used as a measure of DNA synthesis itself, on the assumption that the degree of participation (DP) of TdR in the overall synthesis of deoxythymidine monophosphate in DNA is constant under a variety of conditions. It is now found that in Escherichia coli DP (ratio of exogenous TdR incorporated into DNA to total TdR content of DNA) depends on many factors. In basal medium, DP is 38% in wild… CONTINUE READING

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