Degradation systems in heart failure.

@article{Nishida2015DegradationSI,
  title={Degradation systems in heart failure.},
  author={Kazuhiko Nishida and Osamu Yamaguchi and Kinya Otsu},
  journal={Journal of molecular and cellular cardiology},
  year={2015},
  volume={84},
  pages={
          212-22
        }
}
Heart failure is a complex clinical syndrome that results from any structural or functional impairment of ventricular filling or the ejection of blood, and is a leading cause of morbidity and mortality in industrialized countries. The mechanisms underlying the development of heart failure are multiple, complex and not well understood. Cardiac mass and its homeostasis are maintained by the balance between protein synthesis and degradation, and an imbalance is likely to result in cellular… CONTINUE READING
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