Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.

@article{Sderbom1998DegradationPO,
  title={Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.},
  author={Fredrik S{\"o}derbom and Eric G. Wagner},
  journal={Microbiology},
  year={1998},
  volume={144 ( Pt 7)},
  pages={
          1907-17
        }
}
RNA decay in bacteria is carried out by a number of enzymes that participate in the coordinated degradation of their substrates. Endo- and exonucleolytic cleavages as well as polyadenylation are generally involved in determining the half-life of RNAs. Small, untranslated antisense RNAs are suitable model systems to study decay. A study of the pathway of degradation of CopA, the copy number regulator RNA of plasmid R1, is reported here. Strains carrying mutations in the genes encoding RNase E… CONTINUE READING

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