Degradation of tyrosine and tryptophan residues of peptides by type I photosensitized oxidation.

Abstract

Pterin derivatives are involved in various biological functions, including enzymatic processes that take place in human skin. Unconjugated oxidized pterins are efficient photosensitizers under UV-A irradiation and accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder. These compounds are able to photoinduce the… (More)
DOI: 10.1016/j.jphotobiol.2016.09.024

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