Degradation of rat lung collagens by cathepsin B.


The lysosomal proteinase cathepsin B degrades purified insoluble collagen in vitro. To determine whether the enzyme degrades collagens present in normal extracellular matrices, we quantitated release of hydroxyproline-containing peptides during incubation of rat lung explants with bovine spleen cathepsin B. Incubation of explants with cathepsin B at pH 5.9… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.