Degradation of proline peptides in peptidase-deficient strains of Salmonella typhimurium.

@article{Miller1983DegradationOP,
  title={Degradation of proline peptides in peptidase-deficient strains of Salmonella typhimurium.},
  author={Charles G. Miller and Louis Green},
  journal={Journal of bacteriology},
  year={1983},
  volume={153 1},
  pages={350-6}
}
A mutant strain of Salmonella typhimurium that lacks two proline-specific peptidases (peptidases P and Q) could not complete the degradation of proline peptides formed as intermediates in starvation-induced protein breakdown. The wild-type strain produced free proline as the product of degradation of proline-labeled proteins. The pepP pepQ mutant, however, produced a mixture of small proline peptides. In the absence of peptidase Q only, peptidase P could complete the degradation of most of the… CONTINUE READING