Degradation of oxidized and glycoxidized collagen: role of collagen cross-linking.

@article{Nowotny2014DegradationOO,
  title={Degradation of oxidized and glycoxidized collagen: role of collagen cross-linking.},
  author={Kerstin Nowotny and T. Grune},
  journal={Archives of biochemistry and biophysics},
  year={2014},
  volume={542},
  pages={56-64}
}
Skin aging is a multifactorial process leading to structural and physiological changes. Protein modifications are known to play here an important role. Since collagen is the most abundant protein in the extracellular matrix of the skin and due to its slow turnover rates it is a frequent target of modifications by reactive compounds. Using skin biopsies of… CONTINUE READING