Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiae.

@article{Das2003DegradationON,
  title={Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiae.},
  author={Biswadip Das and James Scott Butler and F. C. Sherman},
  journal={Molecular and cellular biology},
  year={2003},
  volume={23 16},
  pages={
          5502-15
        }
}
A nuclear mRNA degradation (DRN) system was identified from analysis of mRNA turnover rates in nup116-Delta strains of Saccharomyces cerevisiae lacking the ability to export all RNAs, including poly(A) mRNAs, at the restrictive temperature. Northern blotting, in situ hybridization, and blocking transcription with thiolutin in nup116-delta strains revealed a rapid degradation of mRNAs in the nucleus that was suppressed by the rrp6-delta, rai1-delta, and cbc1-delta deletions, but not by the upf1… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 67 CITATIONS, ESTIMATED 55% COVERAGE

Core exosome-independent roles for Rrp6 in cell cycle progression.

  • Molecular biology of the cell
  • 2009
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2004
2019

CITATION STATISTICS

  • 12 Highly Influenced Citations

Similar Papers

Loading similar papers…