Degradation of antidepressant drug fluoxetine in aqueous media by ozone/H2O2 system: process optimization using central composite design.

@article{AghaeinejadMeybodi2015DegradationOA,
  title={Degradation of antidepressant drug fluoxetine in aqueous media by ozone/H2O2 system: process optimization using central composite design.},
  author={Abbas Aghaeinejad-Meybodi and Amanollah Ebadi and Sirous Shafiei and Alireza Khataee and Mohammad Rostampour},
  journal={Environmental technology},
  year={2015},
  volume={36 9-12},
  pages={1477-88}
}
The main objective of this work is the modelling and optimization of antidepressant drug fluoxetine degradation in aqueous solution by ozone/H2O2 process using central composite design. The operational parameters were ozone concentration, initial hydrogen peroxide concentration, reaction time and initial fluoxetine concentration. A good agreement between the predicted values of fluoxetine removal and experimental results were observed (R2=0.976 and Adj-R2=0.955). Pareto analysis indicated that… CONTINUE READING
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