Degradation of Poly(D,L-lactide-co-glycolide) 50:50 Implant in Aqueous Medium

@inproceedings{Farahani2005DegradationOP,
  title={Degradation of Poly(D,L-lactide-co-glycolide) 50:50 Implant in Aqueous Medium},
  author={Tahereh Darestani Farahani and Ali Akbar Entezami and Hamid Mobedi and Mojtaba Abtahi},
  year={2005}
}
rently investigated for making controlled drug delivery devices. In spite of the large number of investigations dealing with LA/GA polymers which have been reported in the literature, only little is known about the degradation mechanism of these polyesters in solid state. In this study poly(L,D-lactide-co-glycolide) 50:50 (PLGA) was hydrolyzed at 37C for periods up to 56 days. PLGA discs were prepared in 60C and the results of their in vitro biodegradation behaviour are reported. We observed… CONTINUE READING