Degradation of 1,2-dibromoethane by Mycobacterium sp. strain GP1.

  title={Degradation of 1,2-dibromoethane by Mycobacterium sp. strain GP1.},
  author={Gerrit J Poelarends and Johan E. T. van Hylckama Vlieg and Julian R. Marchesi and Luisa M Freitas dos Santos and Dick B. Janssen},
  journal={Journal of bacteriology},
  volume={181 7},
The newly isolated bacterial strain GP1 can utilize 1, 2-dibromoethane as the sole carbon and energy source. On the basis of 16S rRNA gene sequence analysis, the organism was identified as a member of the subgroup which contains the fast-growing mycobacteria. The first step in 1,2-dibromoethane metabolism is catalyzed by a hydrolytic haloalkane dehalogenase. The resulting 2-bromoethanol is rapidly converted to ethylene oxide by a haloalcohol dehalogenase, in this way preventing the accumulation… CONTINUE READING


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  • E. J. Bower, P. L. McCarthy
  • Nucleic Acids Res .
  • 1997

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