Degradation and erosion mechanisms of bioresorbable porous acellular vascular grafts: an in vitro investigation.

@article{Gade2017DegradationAE,
  title={Degradation and erosion mechanisms of bioresorbable porous acellular vascular grafts: an in vitro investigation.},
  author={Piyusha S Gade and Keewon Lee and Blaise N. Pfaff and Yadong Wang and Anne M Robertson},
  journal={Journal of the Royal Society, Interface},
  year={2017},
  volume={14 132}
}
A fundamental mechanism of in situ tissue regeneration from biodegradable synthetic acellular vascular grafts is the effective interplay between graft degradation, erosion and the production of extracellular matrix. In order to understand this crucial process of graft erosion and degradation, we conducted an in vitro investigation of grafts (n = 4 at days 1, 4, 7, 10 each) exposed to enzymatic degradation. Herein, we provide constitutive relationships for mass loss and mechanical properties… CONTINUE READING

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