Degradability in vitro of polyurethanes based on synthetic atactic poly[(R,S)-3-hydroxybutyrate].

@article{Brzeska2015DegradabilityIV,
  title={Degradability in vitro of polyurethanes based on synthetic atactic poly[(R,S)-3-hydroxybutyrate].},
  author={Joanna Brzeska and Henryk Janeczek and Helena Janik and Marek M Kowalczuk and Maria Rutkowska},
  journal={Bio-medical materials and engineering},
  year={2015},
  volume={25 2},
  pages={117-25}
}
The aim of the present study was to determine the degradability of aliphatic polyurethanes, based on a different amount of synthetic, atactic poly[(R,S)-3-hydroxybutyrate] (a-PHB), in hydrolytic (phosphate buffer) and oxidative (H2O2/CoCl2) solutions. The soft segments were built with atactic poly[(R,S)-3-hydroxybutyrate] and polycaprolactone or polyoxytetramethylenediols, whereas hard segments were the reaction product of 4,4'-methylenedicyclohexyl diisocyanate and 1,4-butanediol.The selected… CONTINUE READING

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