Degenerative grade affects the responses of human nucleus pulposus cells to link-N, CTGF, and TGFβ3.

@article{Abbott2013DegenerativeGA,
  title={Degenerative grade affects the responses of human nucleus pulposus cells to link-N, CTGF, and TGFβ3.},
  author={Rosalyn Delia Abbott and Devina Purmessur and Robert Daniel Monsey and David R Brigstock and Damien M. Laudier and James C Iatridis},
  journal={Journal of spinal disorders & techniques},
  year={2013},
  volume={26 3},
  pages={E86-94}
}
STUDY DESIGN Cells isolated from moderately and severely degenerated human intervertebral disks (IVDs) cultured in an alginate scaffold. OBJECTIVE To compare the regenerative potential of moderately versus severely degenerated cells using 3 proanabolic stimulants. SUMMARY OF BACKGROUND DATA Injection of soluble cell signaling factors has potential to slow the progression of IVD degeneration. Although degenerative grade is thought to be an important factor in targeting therapeutic… CONTINUE READING
9 Citations
37 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Similar Papers

Loading similar papers…