Deformation and collapse of microtubules on the nanometer scale.


We probe the local mechanical properties of microtubules at the nanometer scale by radial indentation with a scanning force microscope tip. We find a linear elastic regime that can be described by both thin-shell theory and finite element methods, in which microtubules are modeled as hollow tubes. We also find a nonlinear regime and catastrophic collapse of… (More)


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@article{Pablo2003DeformationAC, title={Deformation and collapse of microtubules on the nanometer scale.}, author={Pedro Jose de Pablo and Iwan A T Schaap and Fred C MacKintosh and Christoph F Schmidt}, journal={Physical review letters}, year={2003}, volume={91 9}, pages={098101} }