• Computer Science, Medicine
• Published in Medical Image Analysis 2005
• DOI:10.1016/j.media.2006.06.005

Deformable registration of brain tumor images via a statistical model of tumor-induced deformation

@article{Mohamed2005DeformableRO,
  title={Deformable registration of brain tumor images via a statistical model of tumor-induced deformation},
  author={Ashraf Mohamed and Evangelia I. Zacharaki and Dinggang Shen and Christos Davatzikos},
  journal={Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention},
  year={2005},
  volume={8 Pt 2},
  pages={
          263-70
        }
}

• Ashraf Mohamed, Evangelia I. Zacharaki, +1 author Christos Davatzikos

An approach to deformable registration of three-dimensional brain tumor images to a normal brain atlas is presented. The approach involves the integration of three components: a biomechanical model of tumor mass-effect, a statistical approach to estimate the model's parameters, and a deformable image registration method. Statistical properties of the desired deformation map are first obtained through tumor mass-effect simulations on normal brain images. This map is decomposed into the sum of… CONTINUE READING

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