Deformability Calculation for Estimation of the Relative Stability of Chemically Modified RNA Duplexes.

Abstract

Chemical modification of RNA duplexes alters their stability. We have attempted to develop a computational approach to estimate the thermal stability of chemically modified duplexes. These studies revealed that the deformability of chemically modified RNA duplexes, calculated from molecular dynamics simulations, could be used as a good indicator for… (More)
DOI: 10.1002/cpnc.25

Cite this paper

@article{Masaki2017DeformabilityCF, title={Deformability Calculation for Estimation of the Relative Stability of Chemically Modified RNA Duplexes.}, author={Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, journal={Current protocols in nucleic acid chemistry}, year={2017}, volume={68}, pages={7.27.1-7.27.10} }