Definitive radiation therapy in the management of symptomatic patients with optic glioma. Survival and long-term effects.

@article{Pierce1990DefinitiveRT,
  title={Definitive radiation therapy in the management of symptomatic patients with optic glioma. Survival and long-term effects.},
  author={Stephanie M. Pierce and Patrick D. Barnes and Jay Steven Loeffler and Cornelius J. Mcginn and Nancy J. Tarbell},
  journal={Cancer},
  year={1990},
  volume={65 1},
  pages={45-52}
}
We reviewed 24 children who had symptomatic gliomas that involved the optic chiasm and were treated with definitive radiation therapy from 1971 to 1986. In eight patients (33%), histologic confirmation of low-grade astrocytoma was obtained. Patients had radiation therapy only if there was evidence of visual deterioration or other clinical or radiographic evidence of disease progression. Radiation doses ranged from 4500 to 5660 cGy (median, 5400 cGy) with up to a 17-year follow-up period (median… CONTINUE READING