Definition of mean residence times in pharmacokinetics.

  title={Definition of mean residence times in pharmacokinetics.},
  author={David J. Cutler},
  journal={Biopharmaceutics & drug disposition},
  volume={8 1},
A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedures for using urinary excretion data in mean residence time estimation are discussed.