Definition of a C-reactive protein binding determinant on histones.

  title={Definition of a C-reactive protein binding determinant on histones.},
  author={Terry W. Du Clos and Lorna T. Zlock and Lorraine L. Marnell},
  journal={The Journal of biological chemistry},
  volume={266 4},
C-reactive protein (CRP) is an acute phase inflammatory protein in man which binds to phosphocholine, chromatin, histones, and the 70-kDa protein of the U1 small nuclear ribonucleoprotein particle in a calcium-dependent, phosphocholine-inhibitable manner. CRP also binds to other proteins including fibronectin. The determinants involved in CRP binding to these diverse proteins have not been identified. The binding of CRP to histones was examined as these proteins are available in large quantity… CONTINUE READING
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