Definition and polarity of action of DNA replication terminators in Bacillus subtilis.

@article{Smith1992DefinitionAP,
  title={Definition and polarity of action of DNA replication terminators in Bacillus subtilis.},
  author={Michael A. Smith and R Gerry Wake},
  journal={Journal of molecular biology},
  year={1992},
  volume={227 3},
  pages={648-57}
}
The first stage in termination of chromosome replication in Bacillus subtilis involves arrest of the clockwise fork at the inverted repeat region (IRR), comprising the opposed IRI and IRII sequences, adjacent to the upstream region of the rtp gene, which encodes the replication terminator protein RTP. RTP binds to IRI and IRII. The ability of the IRR and its components to function as terminators, in conjunction with RTP, and their polarity of action have now been tested by the use of plasmids… CONTINUE READING

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