Definition and pathology of primary sclerosing cholangitis.

  title={Definition and pathology of primary sclerosing cholangitis.},
  author={Yasuni Nakanuma and Kenichi Harada and Kazuyoshi Katayanagi and Koichi Tsuneyama and Motoko Sasaki},
  journal={Journal of hepato-biliary-pancreatic surgery},
  volume={6 4},
Although primary sclerosing cholangitis (PSC) is not a common disease, it is important in the differential diagnosis of hepatobiliary tract diseases in clinical practice. A diagnosis of PSC should be made only after the exclusion of similar diseases with well known etiologies or pathogeneses. In this review, the pathology of classical PSC and its variants or related diseases is highlighted. PSC is histologically characterized by progressive periductal fibrosis with luminal stenosis or… CONTINUE READING