Definition and classification of cancer cachexia: an international consensus.

  title={Definition and classification of cancer cachexia: an international consensus.},
  author={Kenneth C. H. Fearon and Florian Strasser and Stefan D. Anker and Ingvar Bosaeus and E Bruera and Robin L. Fainsinger and Aminah Jatoi and Charles M Loprinzi and Neil Macdonald and Giovanni Mantovani and Mellar Davis and Maurizio Muscaritoli and Faith D. Ottery and Lukas Radbruch and Paula Ravasco and Declan Walsh and Andrew Wilcock and Stein Kaasa and Vickie Baracos},
  journal={The Lancet. Oncology},
  volume={12 5},
To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. Its pathophysiology is characterised by a negative… CONTINUE READING