Definition and Classification of Acute Kidney Injury

  title={Definition and Classification of Acute Kidney Injury},
  author={John A. Kellum and Rinaldo Bellomo and Claudio Ronco},
  journal={Nephron. Clinical practice},
  volume={109 4},
Changes in urine output and glomerular filtration rate are neither necessary nor sufficient for the diagnosis of renal pathology. Yet no simple alternative for the diagnosis currently exists. Until recently, there has been no consensus as to diagnostic criteria or clinical definition of acute renal failure. Depending on the definition used, acute renal failure has been reported to affect from 1 to 25% of ICU patients and has led to mortality rates from 15 to 60%. The RIFLE criteria were… CONTINUE READING


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