Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

@article{She2008DefinitionCA,
  title={Definition, conservation and epigenetics of housekeeping and tissue-enriched genes},
  author={Xinwei She and Carol A. Rohl and John C. Castle and Amit V. Kulkarni and Jason M. Johnson and Ronghua Chen},
  journal={BMC Genomics},
  year={2008},
  volume={10},
  pages={269 - 269}
}
Housekeeping genes (HKG) are constitutively expressed in all tissues while tissue-enriched genes (TEG) are expressed at a much higher level in a single tissue type than in others. HKGs serve as valuable experimental controls in gene and protein expression experiments, while TEGs tend to represent distinct physiological processes and are frequently candidates for biomarkers or drug targets. The genomic features of these two groups of genes expressed in opposing patterns may shed light on the… CONTINUE READING

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Housekeeping genes ( HKG ) are constitutively expressed in all tissues while tissue - enriched genes ( TEG ) are expressed at a much higher level in a single tissue type than in others .
Housekeeping genes ( HKG ) are constitutively expressed in all tissues while tissue - enriched genes ( TEG ) are expressed at a much higher level in a single tissue type than in others .
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