Defining the multivalent functions of CTCF from chromatin state and three-dimensional chromatin interactions

Abstract

CCCTC-binding factor (CTCF) is a multi-functional protein that is assigned various, even contradictory roles in the genome. High-throughput sequencing-based technologies such as ChIP-seq and Hi-C provided us the opportunity to assess the multivalent functions of CTCF in the human genome. The location of CTCF-binding sites with respect to genomic features… (More)
DOI: 10.1093/nar/gkw249

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