Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells.

@article{Canella2010DefiningTR,
  title={Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells.},
  author={Donatella Canella and Viviane Praz and Jaime H. Reina and Pascal Cousin and Nouria Hernandez},
  journal={Genome research},
  year={2010},
  volume={20 6},
  pages={710-21}
}
Our view of the RNA polymerase III (Pol III) transcription machinery in mammalian cells arises mostly from studies of the RN5S (5S) gene, the Ad2 VAI gene, and the RNU6 (U6) gene, as paradigms for genes with type 1, 2, and 3 promoters. Recruitment of Pol III onto these genes requires prior binding of well-characterized transcription factors. Technical limitations in dealing with repeated genomic units, typically found at mammalian Pol III genes, have so far hampered genome-wide studies of the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 61 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

association with the vault complex

  • Z Wang, RG Roeder
  • J Biol Chem
  • 1995
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…