Defining the Molecular Recognition of Globo H (Human Breast Cancer) Antigen Through Probe Structures Prepared by Total Synthesis.

@article{Kim1996DefiningTM,
  title={Defining the Molecular Recognition of Globo H (Human Breast Cancer) Antigen Through Probe Structures Prepared by Total Synthesis.},
  author={I. J. Kim and Tae Kyo Park and Shuanghua Hu and Kofi Abrampah and S. Zhang and Philip O. Livingston and Samuel J Danishefsky},
  journal={ChemInform},
  year={1996},
  volume={27}
}
7 Citations
Adenovirus by Delivery of Virus in a Generate CTL in Mice Immune to Cutting Edge: Restoration of the Ability to
TLDR
Gelfoam enhances CTL activation by recombinant viral vectors in a setting where preformed Ab to the virus is present and also in a tolerant self-Ag model.
Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1
TLDR
The discovery that a systemic human ribonuclease binds to a moiety displayed on human cancer cells links two clinical paradigms and suggests a mechanism for innate resistance to cancer.
Carbohydrate vaccines as immunotherapy for cancer
TLDR
Methods to enhance immunological recognition and induction of immunity in vivo are under investigation, including defining the appropriate tumour‐associated antigen, successfully synthesizing the antigen to mimic the original molecule, inducing an immune response, and subsequently enhancing the immunological reactivity so that all components can work together.
Immunotherapy and prostate cancer.
Cutting Edge: Restoration of the Ability to Generate CTL in Mice Immune to Adenovirus by Delivery of Virus in a Collagen-Based Matrix
TLDR
The data show that coinjection of Gelfoam with type 5 adenovirus recombinant for prostate-specific Ag (Ad5-PSA) enhanced CTL activation and enhanced immunization in a self-Ag model and also in a tolerant self- Ag model.
Integrin – ligandbindingproperties governcellmigrationspeed throughcell – substratum adhesiveness
TLDR
Integrin–ligandbindingproperties governcellmigrationspeed throughcell–substratum adhesiveness and triangle symbols in Figs 1a, 2a, 3a and 4a failed to reproduce satisfactorily.
Carbohydrate antigens as targets for active specific immunotherapy
  • G. Ragupathi
  • Biology, Medicine
    Cancer Immunology, Immunotherapy
  • 1996
Abstract Carbohydrate antigens such as GM2, GD2 and GD3 (gangliosides), Lewisy and globo-H (neutral glycolipids and glycoproteins), and Tn, TF and sTn (glycoproteins) are overexpressed in a variety