Defining target antigens in linear IgA disease using skin from subjects with inherited epidermolysis bullosa as a substrate for indirect immunofluorescence microscopy.

@article{Harman1999DefiningTA,
  title={Defining target antigens in linear IgA disease using skin from subjects with inherited epidermolysis bullosa as a substrate for indirect immunofluorescence microscopy.},
  author={Karen E Harman and Balbir S. Bhogal and Robin A. J. Eady and J A McGrath and Martin M. Black},
  journal={The British journal of dermatology},
  year={1999},
  volume={141 3},
  pages={475-80}
}
Identification of target antigens in immunobullous disorders usually involves laborious techniques such as immunoblotting and immunoprecipitation, which do not always provide conclusive data. This is particularly true of linear IgA disease (LAD) in which the target antigen has often proved difficult to identify. As an alternative means of antigen… CONTINUE READING