Defining structural domains of an intrinsically disordered protein: Sic1, the cyclin-dependent kinase inhibitor of Saccharomyces cerevisiae.

@article{Brocca2011DefiningSD,
  title={Defining structural domains of an intrinsically disordered protein: Sic1, the cyclin-dependent kinase inhibitor of Saccharomyces cerevisiae.},
  author={Stefania Brocca and Lorenzo Testa and M{\'a}ria {\vS}amal{\'i}kov{\'a} and Rita Grandori and Marina Lotti},
  journal={Molecular biotechnology},
  year={2011},
  volume={47 1},
  pages={34-42}
}
The cyclin-dependent kinase inhibitor Sic1 is an intrinsically disordered protein (IDP) involved in cell-cycle regulation in the yeast Saccharomyces cerevisiae. Notwithstanding many studies on its biological function, structural characterization has been attempted only recently, fostering the development of production and purification protocols suitable to… CONTINUE READING