Defining optimal therapy for muscle invasive bladder cancer.

  title={Defining optimal therapy for muscle invasive bladder cancer.},
  author={Harry W. Herr and Zohar A. Dotan and Sherri Machele Donat and Dean F Bajorin},
  journal={The Journal of urology},
  volume={177 2},
PURPOSE We defined an optimal curative strategy for muscle invasive bladder cancer and to determine how best to deliver curative therapy. MATERIALS AND METHODS We reviewed published reports from 1985 to 2006 dealing with the treatment of muscle invasive (stage T2-T4a) bladder cancer. We analyzed all cohort, phase II and randomized phase III studies providing level 1 to 3 evidence impacting survival. RESULTS Cisplatin based chemotherapy combined with high quality radical cystectomy and… CONTINUE READING


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