Defining optimal initial therapy for primary CNS lymphoma.

Primary B-cell CNS lymphoma (PCNSL) is a rare disease, with an incidence of four new cases per million per year in the USA. The disease has at least two epidemiological subsets: immunocompromised patients in whom many cases are preceded by Epstein-Barr virus infection, and the more common setting of immunocompetent patients without known risk factors. In… CONTINUE READING