Defining molecular targets to prevent Alzheimer disease.

  title={Defining molecular targets to prevent Alzheimer disease.},
  author={Dennis J Selkoe},
  journal={Archives of neurology},
  volume={62 2},
A n explosion of new techniques to explore DNA and protein biology during the last 2 decades has illuminated one of the most enigmatic and intractable subjects in biomedicine—neurodegeneration. Eponymic diseases of the nervous system that were until recently characterized by mechanistic ignorance and therapeutic nihilism are falling steadily to the power of molecular genetics, cell biology, biochemistry, and animal modeling. Alzheimer, Huntington, Creutzfeld-Jacob, and Parkinson diseases, as… CONTINUE READING
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